Skip to main content

Ubiquinol With 100% Pure Kaneka QH®


NW10007-BottleFront-thumbnail.pngWhat is Ubiquinol?

Ubiquinol is the activated form of coenzyme Q10 (CoQ10)—also known as ubiquinone, which comes from the word "ubiquitous," meaning everywhere. It exists in nearly every cell of your body and in all forms of animal life. Ubiquinone is produced naturally by your body and used to create ATP (energy) in the mitochondria of every cell of your body. Without CoQ10, your body would be unable to produce or sustain energy. Ubiquinol is the activated form of coenzyme 10, or CoQ10.


Levels of Ubiquinol decline with aging, because our bodies are less effective in converting it from Ubiquinone. Clinical evidence suggests that Ubiquinol supplementation helps maintain cardiovascular health and prevent free radical cell damage.*


NatureWise Ubiquinol comprises 100% Pure Kaneka QH® Ubiquinol, the only commercially stable and active form of Ubiquinol available. It was developed by the Kaneka Corporation after decades of research and development. Organic extra virgin olive oil and medium chain triglycerides (MCTs) are added to help with the absorption of the supplement, since Ubiquinol is fat-soluble.

FDA Disclaimer About Health Claims


Please note that the following statement is required to accompany a health claim, such as “may help “maintain cardiovascular health and prevent free radical cell damage.*” It appears on all NatureWise labels and sales copy.

*These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

What is Ubiquinol Used For?

Supportive evidence suggests that regular supplementation with Ubiquinol can supply necessary energy for cells, provide nervous system support, reduce oxidative stress, and promote cardiovascular health.

Why Do We Need to Supplement With Ubiquinol?

In order to product energy, CoQ10 must first be converted into Ubiquinol. In their 20s, most healthy people can readily produce all of the CoQ10 they need and efficiently convert it into Ubiquinol. As we get older, CoQ10 production and conversion to Ubiquinol progressively declines in all the organs and tissues throughout your body, a fact that scientists attribute as one of the causes of fatigue and the decline in stamina and energy often associated with aging.*

Why not just take CoQ10 (Ubiquinone) instead of Ubiquinol? 

Remember that the ability to convert CoQ10 into Ubiquinol declines as we age. In addition,Ubiquinol more easily dissolves in water. This means it can disperse through the cells of the mitochondria more easily than CoQ10, and thus can be better absorbed by the body. Studies have shown that people taking Ubiquinol had higher concentrations of the antioxidant in their blood levels than those taking CoQ10.

What is the suggested use? 

The suggested use for NatureWise Ubiquinol is as follows:

  • Adults take 1 softgel one to three times daily with meals, or as recommended by your healthcare provider.

Is Ubiquinol safe?  

The information from studies done to date suggest that Ubiquinol issafe* when taken according to instructions.

Long-term use

Ubiquinol has been safely used in studies lasting up to 30 months. 

Pregnancy and breast-feeding  

Research shows that the use of Ubiquinol 100 mg twice daily has been safely used during pregnancy, starting at 20 weeks until term.

Women who are breast-feeding should avoid use, since there is insufficient reliable information in this population.

What adverse reactions or side effects are reported with Ubiquinol? 

Orally, coenzyme Q-10 is generally well-tolerated. In clinical studies, there have been no reports of significant adverse effects.  Very rare side effects include nausea, vomiting, diarrhea, appetite suppression, heartburn. These can be minimized by reducing the total daily amounts or splitting the dosage.

Are there any drug or herb interactions reported with Ubiquinol?  

Most herbs and supplements have not been thoroughly tested for interactions with other herbs, supplements, drugs, or foods. Although by no means an exhaustive list, the interactions listed below are based on reports in scientific publications, laboratory experiments, or traditional use. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new medication or supplement.



  • Antihypertensive drugs

  • Chemotherapy

  • Warfarin (Coumadin)

Herbs/dietary supplements 

Ubiquinol may reduce blood pressure, so combining it with other herbs and supplements with the same impact is not recommended. Andrographis, casein peptides, cat's claw, fish oil, L-arginine, lycium, stinging nettle, and theanine are also thought to promote hypotension (low blood pressure) .

Other herbs and supplements that may interact with Ubiquinol 

  • Red yeast

  • Vitamin K

If a drug or dietary supplement is not on the list, does this mean there are no interactions?  

The drug you inquired about is not listed on our current list of known interactions. We strongly recommend that you consult your physician regarding your personal healthcare needs.

Are there any disease interactions reported with Ubiquinol?

  • Hypotension/hypertension

  • Smoking

  • Surgery (can affect blood pressure)​

Are there any food interactions reported with Ubiquinol?

There are none reported.

What else do I need to know about NatureWise Ubiquinol?

NatureWiseUbiquinol is manufactured in the USA, using non-GMO, and gluten-free ingredients.

Each softgel capsule contains 100% Kaneka QH® Ubiquinol. The capsule is composed of bovine gelatin, glycerin, and water. ​Other ingredients include organic chain triglycerides (MCT), rosemary oil extract, yellow beeswax, sunflower lecithin, and ascorbyl palmitate. NatureWise Ubiquinol contains no yeast, wheat, gluten, dairy, corn, soy, eggs, sugar, tree nuts, peanuts, fish, shellfish, or hydrogenated oils.


*Please note that our Ubiquinol supplements are no longer certified as kosher.

What provides the MCTs (medium chain triglycerides) in Ubiquinol?

Edit section

The Medium Chain Triglycerides (MCT's) in Ubiquinol are derived from palm oil.

Why is rosemary oil extract included under Other Ingredients?

Edit section

As the activated form of CoQ10, Ubiquinol is quite unstable and can easily become oxidized if not properly encapsulated. Rosemary oil extract is a natural antioxidant added to our NatureWise Ubiquinol capsules to preserve the capsule's ingredients and to protect them from oxidation. Other Ubiquinol brands often choose not to include natural preservatives, like rosemary oil, because of the added cost to manufacture products with additional antioxidant ingredients.

Why is yellow beeswax included under Other Ingredients?

Edit section

Beeswax is an ingredient commonly used in the majority of Ubiquinol and CoQ10 supplements. Its purpose is to produce a uniform texture within the softgel, and help prevent the separation of ingredients. Because we try to use the most natural ingredients, our NatureWise Ubiquinol capsules contain yellow beeswax, which has not been bleached or treated with alcohol.


How does the olive oil in Ubiquinol supplements keep from going bad?

Edit section
Edit section

Oxidation, through exposure to the air, is the most common reason consumable oils may spoil. Once the pharmaceutical grade, organic olive oil used in our NatureWise Ubiquinol is encapsulated in softgels, there is no exposure to air or risk of oxidation when stored properly and consumed by the expiration date.

Should Ubiquinol be stored in the refrigerator?

Edit section
Edit section

We do not recommend refrigeration since cold temperatures may make the softgels brittle and thus prone to leakage. NatureWise Ubiquinol should be stored in a cool, dry place, away from direct UV light.

  • Was this article helpful?